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The antibody against PNMT was raised in rabbit using the Human PNMT as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against PNMT was raised in rabbit using the Human PNMT as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52315A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PNMT |
| Target Synonyms | Noradrenaline N-methyltransferase antibody; PENT antibody; Phenylethanolamine N-methyltransferase antibody; PNMT antibody; PNMT_HUMAN antibody; PNMTase antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human PNMT | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P11086 |
Uniprot Id
P11086
Target Species
Human
Target Name
PNMT
Target Full Name
Phenylethanolamine N-methyltransferase
Target Function
Converts noradrenaline to adrenaline.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, NNMT/PNMT/TEMT family
Target Synonyms
Noradrenaline N-methyltransferase; PENT; Phenylethanolamine N-methyltransferase; PNMT; PNMT_HUMAN; PNMTase
Target Background
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
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