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The antibody against OSTM1 was raised in rabbit using the Human OSTM1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against OSTM1 was raised in rabbit using the Human OSTM1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52471A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OSTM1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human OSTM1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86WC4 |
Uniprot Id
Q86WC4
Target Species
Human
Target Name
OSTM1
Target Full Name
Osteopetrosis-associated transmembrane protein 1
Target Function
Required for osteoclast and melanocyte maturation and function.
Target Involvement
Osteopetrosis, autosomal recessive 5 (OPTB5)
Target Subcellular Location
Lysosome membrane; Single-pass type I membrane protein. Note=Requires CLCN7 to travel to lysosomes.
Target Protein Families
OSTM1 family
Target Synonyms
Chloride channel 7 beta subunit; GAIP-interacting protein N terminus; GIPN; GL; Grey lethal osteopetrosis; HSPC019; OPTB5; Osteopetrosis-associated transmembrane protein 1; Ostm1; OSTM1_HUMAN; OTTHUMP00000016938; OTTHUMP00000196342
Target Background
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
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