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Rabbit anti-Human CNP Polyclonal Antibody

The antibody against CNP was raised in rabbit using the Human CNP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-52534A

The antibody against CNP was raised in rabbit using the Human CNP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-52534A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCNP
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman CNPTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP09543
Background Information
  • Uniprot Id

    P09543

  • Target Species

    Human

  • Target Name

    CNP

  • Target Full Name

    2',3'-cyclic-nucleotide 3'-phosphodiesterase

  • Target Function

    May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.

  • Target Subcellular Location

    Membrane; Lipid-anchor. Melanosome. Note=Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

  • Target Protein Families

    2H phosphoesterase superfamily, CNPase family

  • Target Synonyms

    CNP1; HLD20; CNPase

  • Target Background

    Predicted to enable 2', 3'-cyclic-nucleotide 3'-phosphodiesterase activity. Involved in substantia nigra development. Located in several cellular components, including extracellular space; microtubule; and plasma membrane. Implicated in hypomyelinating leukodystrophy 20; multiple sclerosis; and schizophrenia. Biomarker of alcoholic liver cirrhosis; multiple sclerosis; and restless legs syndrome.

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