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The antibody against L3MBTL3 was raised in rabbit using the Human L3MBTL3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against L3MBTL3 was raised in rabbit using the Human L3MBTL3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52904A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | L3MBTL3 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human L3MBTL3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96JM7 |
Uniprot Id
Q96JM7
Target Species
Human
Target Name
L3MBTL3
Target Full Name
Lethal(3)malignant brain tumor-like protein 3
Target Function
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells.
Target Subcellular Location
Nucleus.
Target Synonyms
L3MBTL3; H-l(3)mbt-like protein 3; Hl(3)mbt like protein; KIAA1798; l(3)mbt like 3 (Drosophila); l(3)mbt like 3; L(3)mbt like 3 protein; L(3)mbt-like protein 3; L3mbtl3; Lethal(3)malignant brain tumor like 3 protein; Lethal(3)malignant brain tumor-like protein 3; LMBL3_HUMAN; MBT-1; MBT1; RP11-73O6.1
Target Background
This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma.
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