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Rabbit anti-Human ABCB9 Polyclonal Antibody

The antibody against ABCB9 was raised in rabbit using the Human ABCB9 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-54235A

The antibody against ABCB9 was raised in rabbit using the Human ABCB9 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-54235A ClonalityPolyclonal
Host SpeciesRabbitTarget NameABCB9
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman ABCB9Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NP78
Background Information
  • Uniprot Id

    Q9NP78

  • Target Species

    Human

  • Target Name

    ABCB9

  • Target Full Name

    ABC-type oligopeptide transporter ABCB9

  • Target Function

    ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen for degradation. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Binds and transports smaller and larger peptides with the same affinity. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored.

  • Target Subcellular Location

    Lysosome membrane; Multi-pass membrane protein.

  • Target Protein Families

    ABC transporter superfamily, ABCB family, MHC peptide exporter (TC 3.A.1.209) subfamily

  • Target Tissue Specificity

    Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages.

  • Target Synonyms

    ABCB9; KIAA1520ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ABC transporter 9 protein; hABCB9; TAP-like protein; TAPL

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