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The antibody against Abrin-a was raised in rabbit using the Recombinant Abrus precatorius Abrin-a protein (1-251aa ) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.
The antibody against Abrin-a was raised in rabbit using the Recombinant Abrus precatorius Abrin-a protein (1-251aa ) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in Recombinant protein | All lanes: Abrin-a antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 33 kDa | Observed band size: 33 kDa
| Cat.No | ADC-55264A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Abrin-a |
| Target Synonyms | Abrin-a [Cleaved into: Abrin-a A chain (EC 3.2.2.22) (rRNA N-glycosidase); Linker peptide; Abrin-a B chain] | Form | Liquid |
| Species Reactivity | Abrus precatorius | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Abrus precatorius Abrin-a protein (1-251aa ) | Target Species | Abrus precatorius (Indian licorice) (Glycine abrus) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P11140 |
Uniprot Id
P11140
Target Species
Abrus precatorius
Target Function
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis.
Target Protein Families
Ribosome-inactivating protein family, Type 2 RIP subfamily
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