Rabbit anti-Arabidopsis thaliana EIN2 Polyclonal Antibody

Uniprot Id

Q9S814

Target Species

Arabidopsis thaliana

Target Name

EIN2

Target Function

Central factor in signaling pathways regulated by ethylene (ET), and involved in various processes including development, plant defense, senescence, nucleotide sugar flux, and tropisms. Necessary for ethylene-mediated gene regulation, and for the induction of some genes by ozone. Acts downstream of ET receptors, and upstream of ethylene regulated transcription factors. Required for cytokinin-mediated processes. Seems to be implicated in cross-talk between ET, jasmonate and other pathways. Probably not involved in iron uptake. Has a short half-life and undergoes rapid proteasome-mediated turnover in the absence of ethylene. Required for ethylene-induced EIN3 stabilization via proteasomal degradation of EBF1/EBF2 proteins. Regulates the leaf senescence induced by methyl jasmonate, ethylene and abscisic acid (Ref.17, PubMed:15010611). Required during salt stress to confer resistance.; Trafficking signal inducing ethylene response. The nuclear localization is both necessary and sufficient to activate EIN3-mediated transcription and ethylene responses. Necessary and sufficient for 3'-UTR-mediated translational repression of EBF1 and EBF2 mRNAs. Ethylene induces EIN2-CEND to associate with 3' UTRs in cytoplasmic foci and target EBF1/2 mRNAs to cytoplasmic processing-body (P-body). MPK6 regulates the cleavage and nuclear translocation of EIN2-CEND under methyl jasmonate treatment. Required for EIN3 accumulation.

Target Subcellular Location

[Ethylene-insensitive protein 2]: Endoplasmic reticulum membrane; Multi-pass membrane protein.; [EIN2-CEND]: Nucleus. Cytoplasm. Endoplasmic reticulum membrane.

Target Protein Families

NRAMP (TC 2.A.55) family

Target Tissue Specificity

[EIN2-CEND]: Localized to the guard cells after methyl jasmonate treatment.