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The antibody against TFF3 was raised in mouse using the Recombinant Human Trefoil factor 3 as the immunogen. This antibody exists as a non-conjugated isotype IgG2a, purified by protein G purifed . This antibody has been validated on ELISA, IHC, IF.
The antibody against TFF3 was raised in mouse using the Recombinant Human Trefoil factor 3 as the immunogen. This antibody exists as a non-conjugated isotype IgG2a, purified by protein G purifed . This antibody has been validated on ELISA, IHC, IF.
$350.00
Immunohistochemical of paraffin-embedded human colon cancer using TFF3 Monoclonal Antibody at dilution of 1:50
Immunofluorescent analysis of MCF-7 cells using TFF3 Monoclonal Antibody at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L)2
| Cat.No | ADC-55480A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Mouse | Target Name | TFF3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG2a | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Trefoil factor 3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q07654 |
Uniprot Id
Q07654
Target Species
Human
Target Name
TFF3
Target Full Name
Trefoil factor 3
Target Function
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
Target Subcellular Location
Secreted, extracellular space, extracellular matrix. Cytoplasm.
Target Tissue Specificity
Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricular, periventricular
Target Research Area
Signal Transduction
Target Synonyms
hITF; hP1.B; Intestinal trefoil factor; ITF; mITF; OTTMUSP00000021729; P1B; Polypeptide P1.B; TFF3; TFF3_HUMAN; TFI; TREFOIL; Trefoil factor (intestinal); Trefoil factor 3
Target Background
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
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