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Mouse anti-Human TUBB1 Monoclonal Antibody

The antibody against TUBB1 was raised in mouse using the Synthetic Peptide as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on ELISA, WB.

ADC-55732A

The antibody against TUBB1 was raised in mouse using the Synthetic Peptide as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on ELISA, WB.

$167.00

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Specifications


Cat.No ADC-55732A ClonalityMonoclonal
Host SpeciesMouseTarget NameTUBB1
Target Synonyms2810484G07Rik antibody; beta 1 tubulin antibody; Beta tubulin 1, beta 1 antibody; tubulin, beta1 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage BufferPH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBSConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic PeptideTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9H4B7
Background Information
  • Uniprot Id

    Q9H4B7

  • Target Species

    Human

  • Target Name

    TUBB1

  • Target Full Name

    Tubulin beta-1 chain

  • Target Function

    Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

  • Target Involvement

    Macrothrombocytopenia, autosomal dominant, TUBB1-related (MAD-TUBB1)

  • Target Subcellular Location

    Cytoplasm, cytoskeleton.

  • Target Protein Families

    Tubulin family

  • Target Tissue Specificity

    Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins.

  • Target Synonyms

    2810484G07Rik; beta 1 tubulin; Beta tubulin 1, class VI; Beta-tubulin; Class VI beta tubulin; dJ543J19.4; M(beta)1; TBB1_HUMAN; TUBB1; Tubulin beta 1 class VI; Tubulin beta-1 chain; Tubulin, beta 1; tubulin, beta1

  • Target Background

    This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.

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