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Mouse anti-Human GFAP Monoclonal antibody

The antibody against GFAP was raised in mouse using the Synthesized peptide derived from human Glial Fibrillary Acidic Protein (GFAP) as the immunogen. This antibody exists as a non-conjugated isotype IgG1, Kappa. The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody has been validated on ELISA, IHC.

ADC-55988A

The antibody against GFAP was raised in mouse using the Synthesized peptide derived from human Glial Fibrillary Acidic Protein (GFAP) as the immunogen. This antibody exists as a non-conjugated isotype IgG1, Kappa. The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-55988A ClonalityMonoclonal
Host SpeciesMouseTarget Namegfap
Target SynonymsGFAP antibody; GFAP Epsilon antibody; GFAP_HUMAN antibody; GFAPdelta antibody; GFAPepsilon antibody; Glial fibrillary acidic protein antibody; Intermediate filament protein antibodyFormLiquid
Species ReactivityHumanIsotypeIgG1, Kappa
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from human Glial Fibrillary Acidic Protein (GFAP)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP14136
Background Information
  • Uniprot Id

    P14136

  • Target Species

    Human

  • Target Name

    GFAP

  • Target Full Name

    Glial fibrillary acidic protein

  • Target Function

    GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

  • Target Involvement

    Alexander disease (ALXDRD)

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Intermediate filament family

  • Target Tissue Specificity

    Expressed in cells lacking fibronectin.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    ALXDRD; GFAP

  • Target Background

    This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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