Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SERPINB4 was raised in rabbit using the Recombinant Human Serpin B4 protein (128-208AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SERPINB4 was raised in rabbit using the Recombinant Human Serpin B4 protein (128-208AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-06769A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SERPINB4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Serpin B4 protein (128-208AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P48594 |
Uniprot Id
P48594
Target Species
Human
Target Name
SERPINB4
Target Full Name
Serpin B4
Target Function
May act as a protease inhibitor to modulate the host immune response against tumor cells.
Target Subcellular Location
Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
Target Protein Families
Serpin family, Ov-serpin subfamily
Target Tissue Specificity
Squamous cells.
Target Research Area
Cancer
Target Synonyms
Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor (leucine serpin); SCCA 2; SCCA-2; SCCA1; SCCA2; SCCA2/SCCA1 fusion protein; Serine (or cysteine) proteinase inhibitor; clade B (ovalbumin); member 4; Serpin B4; Serpin peptidase inhibitor; clade B (ovalbumin); member 4; SERPINB 4; SERPINB4; SPB4_HUMAN; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2
Target Background
The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
