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The antibody against PSAT1 was raised in rabbit using the Recombinant Human Phosphoserine aminotransferase protein (104-206AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against PSAT1 was raised in rabbit using the Recombinant Human Phosphoserine aminotransferase protein (104-206AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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IHC image of PSAT1 Antibody diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system.
| Cat.No | ADC-06802A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PSAT1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosphoserine aminotransferase protein (104-206AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y617 |
Uniprot Id
Q9Y617
Target Species
Human
Target Name
PSAT1
Target Full Name
Phosphoserine aminotransferase
Target Function
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Target Involvement
Phosphoserine aminotransferase deficiency (PSATD); Neu-Laxova syndrome 2 (NLS2)
Target Protein Families
Class-V pyridoxal-phosphate-dependent aminotransferase family, SerC subfamily
Target Tissue Specificity
Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
Target Synonyms
PSA; EPIP; NLS2; PSAT; PSATD; PSAT1
Target Background
This gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, and 8.
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