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The recombinant antibody against FTL was produced using a synthesized peptide derived from Human FTL as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, FC.
The recombinant antibody against FTL was produced using a synthesized peptide derived from Human FTL as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, FC.
$350.00
| Cat.No | ADC-56539A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | FTL | Target Synonyms | Ferritin light chain (Ferritin L subunit), FTL |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, FC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human FTL | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P02792 |
Uniprot Id
P02792
Target Species
Human
Target Name
FTL
Target Full Name
Ferritin light chain
Target Function
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
Target Involvement
Hyperferritinemia with or without cataract (HRFTC); Neurodegeneration with brain iron accumulation 3 (NBIA3); L-ferritin deficiency (LFTD)
Target Protein Families
Ferritin family
Target Research Area
Cardiovascular
Target Synonyms
LFTD; NBIA3; Ferritin Light Chain
Target Background
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
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