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Rabbit anti-Human KRT80 Polyclonal Antibody

The antibody against KRT80 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 242-452 of human KRT80 (NP_872313.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.

ADA-00437A

The antibody against KRT80 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 242-452 of human KRT80 (NP_872313.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.

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Specifications


Cat.No ADA-00437A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKRT80
Target SynonymsKB20; KRT80FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
ApplicationELISA, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 242-452 of human KRT80 (NP_872313.2).Target SpeciesHuman
Uniprot IDQ6KB66Immunogen Sequence
Background Information
  • Uniprot Id

    Q6KB66

  • Target Species

    Human

  • Target Name

    KRT80

  • Target Full Name

    Keratin, type II cytoskeletal 80

  • Target Synonyms

    CK 80; CK-80; CK80; Cytokeratin 80; Cytokeratin-80; K 80; K2C80_HUMAN; K80; KB20; Keratin 80; Keratin; Keratin-80; KRT 80; Krt80; type II cytoskeletal 80; Type II keratin; Type-II keratin Kb20

  • Target Background

    Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.

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