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The antibody against TMOD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human TMOD1 (NP_003266.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TMOD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human TMOD1 (NP_003266.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00459A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMOD1 |
| Target Synonyms | TMOD; ETMOD; D9S57E; TMOD1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, K-562, Mouse lung, Mouse skeletal muscle | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human TMOD1 (NP_003266.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P28289 | Immunogen Sequence |
Uniprot Id
P28289
Target Species
Human
Target Name
TMOD1
Target Full Name
Tropomodulin-1
Target Function
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
Tropomodulin family
Target Tissue Specificity
Highly expressed in the erythrocyte, heart and skeletal muscle.
Target Research Area
others
Target Synonyms
D9S57E; E Tmod ; E tropomodulin; E-Tmod; Erythrocyte tropomodulin; ETMOD; MGC124125; MGC124126; OTTHUMP00000021743 ; TMOD; Tmod1; TMOD1 protein; TMOD1_HUMAN; Tropomodulin 1; Tropomodulin-1
Target Background
This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.
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