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The antibody against GINS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human GINS2 (NP_057179.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GINS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human GINS2 (NP_057179.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01033A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GINS2 |
| Target Synonyms | PSF2; Pfs2; HSPC037; GINS2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 22Rv1, Jurkat, MCF7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human GINS2 (NP_057179.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MDAAEVEFLAEKELVTIIPNFSLDKIYLIGGDLGPFNPGLPVEVPLWLAINLKQRQKCRLLPPEWMDVEKLEKMRDHERKEETFTPMPSPYYMELTKLLLNHASDNIPKADEIRTLVKDMWDTRIAKLRVSADSFVRQQEAHAKLDNLTLMEINTSGTFLTQALNHMYKLRTNLQPLESTQSQDF | Uniprot ID | Q9Y248 |
Uniprot Id
Q9Y248
Target Species
Human
Target Name
GINS2
Target Full Name
DNA replication complex GINS protein PSF2
Target Function
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
GINS2/PSF2 family
Target Research Area
Transcription
Target Synonyms
DNA replication complex GINS protein PSF2; GINS complex subunit 2 (Psf2 homolog); GINS complex subunit 2; gins2; HSPC037; Pfs2; PSF2; PSF2_HUMAN
Target Background
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.
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