Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SPG11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 550-750 of human SPG11 (NP_079413.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SPG11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 550-750 of human SPG11 (NP_079413.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01425A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPG11 |
| Target Synonyms | ALS5; CMT2X; KIAA1840; SPG11 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 550-750 of human SPG11 (NP_079413.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96JI7 | Immunogen Sequence |
Uniprot Id
Q96JI7
Target Species
Human
Target Name
SPG11
Target Full Name
Spatacsin
Target Function
May play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport.
Target Involvement
Spastic paraplegia 11, autosomal recessive (SPG11); Amyotrophic lateral sclerosis 5, juvenile (ALS5); Charcot-Marie-Tooth disease 2X (CMT2X)
Target Subcellular Location
Cytoplasm, cytosol. Nucleus. Cell projection, axon. Cell projection, dendrite.
Target Tissue Specificity
Expressed in all structures of brain, with a high expression in cerebellum. Expressed in cortical projection neurons.
Target Synonyms
Colorectal carcinoma associated protein; Colorectal carcinoma-associated protein; DKFZp762B1512; FLJ21439; KIAA1840; Spastic paraplegia 11 (autosomal recessive); Spastic paraplegia 11; Spastic paraplegia 11 protein; Spatacsin; SPG 11; Spg11; SPTCS_HUMAN
Target Background
The protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
