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Rabbit anti-Human CALY Polyclonal Antibody

The antibody against CALY was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human CALY (NP_056537.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01601A

The antibody against CALY was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human CALY (NP_056537.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01601A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCALY
Target SynonymsNSG3; DRD1IP; CALYFormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human CALY (NP_056537.1).Target SpeciesHuman
Immunogen SequenceMVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPDQQNFPDLEGQRLNCSHPEEGRRLPTARUniprot IDQ9NYX4
Background Information
  • Uniprot Id

    Q9NYX4

  • Target Species

    Human

  • Target Name

    CALY

  • Target Full Name

    Neuron-specific vesicular protein calcyon

  • Target Function

    Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.

  • Target Subcellular Location

    Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.

  • Target Protein Families

    NSG family

  • Target Tissue Specificity

    Expressed in the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics.

  • Target Synonyms

    CALCYON; Caly; CALY_HUMAN; D1 dopamine receptor interacting protein; Drd1ip; Neuron specific vesicular protein calcyon; Neuron-specific vesicular protein calcyon; NSG3; RP11-122K13.5

  • Target Background

    The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs.

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