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The antibody against SRPRB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 57-271 of human SRPRB (NP_067026.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against SRPRB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 57-271 of human SRPRB (NP_067026.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-01650A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRPRB |
| Target Synonyms | APMCF1; SR-beta; SRPRB | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | B cells, HT-29, LO2, MCF7, Mouse liver, Mouse pancreas, Mouse small intestine, Rat liver | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 57-271 of human SRPRB (NP_067026.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y5M8 | Immunogen Sequence |
Uniprot Id
Q9Y5M8
Target Species
Human
Target Name
SRPRB
Target Full Name
Signal recognition particle receptor subunit beta
Target Function
Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families
SRP receptor beta subunit family
Target Synonyms
SRPRB; PSEC0230; Signal recognition particle receptor subunit beta; SR-beta; Protein APMCF1
Target Background
The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.
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