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Rabbit anti-Human HSF2 Polyclonal Antibody

The antibody against HSF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 377-536 of human HSF2 (NP_004497.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02278A

The antibody against HSF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 377-536 of human HSF2 (NP_004497.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-02278A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHSF2
Target SynonymsHSF 2; HSTF 2; HSF2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse heart, LO2, Rat liver, Rat testis, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 377-536 of human HSF2 (NP_004497.1).Target SpeciesHuman
Immunogen SequenceMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTKNNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDSUniprot IDQ03933
Background Information
  • Uniprot Id

    Q03933

  • Target Species

    Human

  • Target Name

    HSF2

  • Target Full Name

    Heat shock factor protein 2

  • Target Function

    DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation.

  • Target Protein Families

    HSF family

  • Target Synonyms

    HSF 2; HSTF 2; HSF2

  • Target Background

    The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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