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The antibody against LSM11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 131-360 of human LSM11 (NP_775762.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against LSM11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 131-360 of human LSM11 (NP_775762.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02450A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LSM11 |
| Target Synonyms | AGS8; LSM11 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, HepG2, HL-60, Jurkat, MCF7, Rat pancreas | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 131-360 of human LSM11 (NP_775762.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P83369 | Immunogen Sequence |
Uniprot Id
P83369
Target Species
Human
Target Name
LSM11
Target Full Name
U7 snRNA-associated Sm-like protein LSm11
Target Function
Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to the Sm-binding site of U7 snRNA.
Target Subcellular Location
Nucleus.
Target Protein Families
SnRNP Sm proteins family
Target Synonyms
LSM11U7 snRNA-associated Sm-like protein LSm11
Target Background
Enables U7 snRNA binding activity. Involved in positive regulation of G1/S transition of mitotic cell cycle. Located in nuclear body. Part of U7 snRNP and telomerase holoenzyme complex. Implicated in Aicardi-Goutieres syndrome.
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