Rabbit anti-Human CSNK1G2 Polyclonal Antibody

The antibody against CSNK1G2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 316-415 of human CSNK1G2 (NP_001310.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02572A

Number

Cat.No	ADA-02572A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CSNK1G2
Target Synonyms	CK1g2; CSNK1G2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	BT-474, HL-60, Mouse brain, Mouse skeletal muscle, Mouse testis, Rat skeletal muscle, SKOV3, SW620	Application	ELISA, WB

Cat.No

ADA-02572A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CSNK1G2

Target Synonyms

CK1g2; CSNK1G2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

BT-474, HL-60, Mouse brain, Mouse skeletal muscle, Mouse testis, Rat skeletal muscle, SKOV3, SW620

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 316-415 of human CSNK1G2 (NP_001310.3).	Target Species	Human
Immunogen Sequence	FDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK	Uniprot ID	P78368

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 316-415 of human CSNK1G2 (NP_001310.3).

Target Species

Human

Immunogen Sequence

FDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK

Uniprot ID

P78368

Background Information

Uniprot Id

P78368
Target Species

Human
Target Name

CSNK1G2
Target Full Name

Casein kinase I isoform gamma-2
Target Function

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.
Target Subcellular Location

Cytoplasm, cell cortex. Cytoplasm.
Target Protein Families

Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily
Target Tissue Specificity

Testis.
Target Synonyms

Casein kinase 1; gamma 2; Casein kinase I isoform gamma 2; Casein kinase I isoform gamma-2; CK1g2; CKI gamma 2; CKI-gamma 2; CSNK1G 2; Csnk1g2; KC1G2_HUMAN
Target Background

Enables protein serine/threonine kinase activity. Involved in peptidyl-serine phosphorylation. Located in membrane.

Rabbit anti-Human CSNK1G2 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human CSNK1G2 Polyclonal Antibody Now

Related Products