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The antibody against VTI1B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human VTI1B (NP_006361.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against VTI1B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human VTI1B (NP_006361.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-02707A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VTI1B |
| Target Synonyms | VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE; VTI1B | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human VTI1B (NP_006361.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UEU0 | Immunogen Sequence |
Uniprot Id
Q9UEU0
Target Species
Human
Target Name
VTI1B
Target Full Name
Vesicle transport through interaction with t-SNAREs homolog 1B
Target Function
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
Target Subcellular Location
Early endosome membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule. Recycling endosome membrane; Single-pass type IV membrane protein.
Target Protein Families
VTI1 family
Target Tissue Specificity
Expressed in all tissues examined.
Target Research Area
Transport
Target Synonyms
HGNC:17793; V SNARE; v-SNARE; Vesicle associated soluble NSF attachment protein receptor; Vesicle transport through interaction with t SNAREs 1B; Vesicle transport through interaction with t SNAREs homolog 1B (yeast); Vesicle transport through interaction with t-SNAREs homolog 1B; Vesicle transport v-SNARE protein Vti1-like 1; VTI1; VTI1 like; Vti1 rp1; VTI1-LIKE; Vti1-rp1; VTI1B; VTI1B_HUMAN; VTI1L; VTI1L1; VTI2
Target Background
Enables SNARE binding activity and chloride channel inhibitor activity. Involved in regulation of protein localization to plasma membrane. Located in several cellular components, including endosome membrane; lysosomal membrane; and perinuclear region of cytoplasm.
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