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The antibody against MYBPC2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 912-1141 of human MYBPC2 (NP_004524.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against MYBPC2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 912-1141 of human MYBPC2 (NP_004524.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-02785A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MYBPC2 |
| Target Synonyms | MYBPC; MYBPCF; fsMyBP-C; MYBPC2 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse skeletal muscle, Rat skeletal muscle | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 912-1141 of human MYBPC2 (NP_004524.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q14324 | Immunogen Sequence |
Uniprot Id
Q14324
Target Species
Human
Target Name
MYBPC2
Target Full Name
Myosin-binding protein C, fast-type
Target Function
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Target Protein Families
Immunoglobulin superfamily, MyBP family
Target Research Area
Signal Transduction
Target Synonyms
C protein, skeletal muscle fast isoform; C-protein; Fast MyBP C; Fast MyBP-C; MGC163408; MYBPC; Mybpc2; MYBPCF; Myosin binding protein C, fast type; Myosin-binding protein C, fast-type; MYPC2_HUMAN; skeletal muscle fast isoform
Target Background
This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively.
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