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The antibody against SLC5A6 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human SLC5A6 (NP_066918.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SLC5A6 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human SLC5A6 (NP_066918.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03025A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC5A6 |
| Target Synonyms | SMVT; COMNB; NERIB; SMVTD; SLC5A6 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HT-29, MCF7 | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human SLC5A6 (NP_066918.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | TVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLPLSCQKRLHCRSYGQDHLDTGLFPEKPRNGVLGDSRDKEAMALDGTAYQGSSSTCILQETSL | Uniprot ID | Q9Y289 |
Uniprot Id
Q9Y289
Target Species
Human
Target Name
SLC5A6
Target Full Name
Sodium-dependent multivitamin transporter
Target Function
Sodium-dependent multivitamin transporter that transports pantothenate, biotin and lipoate. Required for biotin and pantothenate uptake in the instestine. Plays a role in the maintenance of intestinal mucosa integrity, by providing the gut mucosa with biotin. May play a role in the transport of biotin and pantothenate into the brain across the blood-brain barrier. May also be involved in the sodium-dependent transport of iodide ions.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.; Cell membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:solute symporter (SSF) (TC 2.A.21) family
Target Tissue Specificity
Expressed in microvessels of the brain (at protein level). Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
Target Synonyms
SMVT; COMNB; NERIB; SMVTD; SLC5A6
Target Background
Enables biotin transmembrane transporter activity and pantothenate transmembrane transporter activity. Involved in anion transmembrane transport and transport across blood-brain barrier. Located in plasma membrane.
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