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The antibody against TRIM45 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TRIM45 (NP_001139107.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
The antibody against TRIM45 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TRIM45 (NP_001139107.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
Immunofluorescence analysis of L929 cells using TRIM45 Rabbit pAb at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
| Cat.No | ADA-03215A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRIM45 |
| Target Synonyms | RNF99; TRIM45 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TRIM45 (NP_001139107.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H8W5 | Immunogen Sequence |
Uniprot Id
Q9H8W5
Target Species
Human
Target Name
TRIM45
Target Full Name
E3 ubiquitin-protein ligase TRIM45
Target Function
May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
TRIM/RBCC family
Target Tissue Specificity
Expressed in skeletal muscle, brain, heart and pancreas.
Target Synonyms
FLJ13181; RING finger protein 99; RNF99; TRI45_HUMAN; TRIM45; Tripartite motif containing 45; Tripartite motif containing protein 45; Tripartite motif-containing protein 45
Target Background
Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to act upstream of or within bone development. Located in cytosol; intercellular bridge; and nucleoplasm.
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