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The antibody against TARS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TARS2 (NP_079426.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TARS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TARS2 (NP_079426.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03286A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TARS2 |
| Target Synonyms | thrRS; TARSL1; COXPD21; TARS2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | LO2, Mouse brain, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TARS2 (NP_079426.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9BW92 | Immunogen Sequence |
Uniprot Id
Q9BW92
Target Species
Human
Target Name
TARS2
Target Full Name
Threonine--tRNA ligase, mitochondrial
Target Function
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.
Target Involvement
Combined oxidative phosphorylation deficiency 21 (COXPD21)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-II aminoacyl-tRNA synthetase family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
TARS2; TARSL1; Threonine--tRNA ligase; mitochondrial; EC 6.1.1.3; Threonyl-tRNA synthetase; ThrRS; Threonyl-tRNA synthetase-like 1
Target Background
This gene encodes a member of the class-II aminoacyl-tRNA synthetase family. The encoded protein is a mitochondrial aminoacyl-tRNA synthetase. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 4.
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