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Rabbit anti-Human FUT8 Polyclonal Antibody

The antibody against FUT8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 376-575 of human FUT8 (NP_835367.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03341A

The antibody against FUT8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 376-575 of human FUT8 (NP_835367.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03341A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFUT8
Target SynonymsCDGF; CDGF1; FUT8FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, A-549ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 376-575 of human FUT8 (NP_835367.1).Target SpeciesHuman
Immunogen SequenceFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYPTYPEAEKUniprot IDQ9BYC5
Background Information
  • Uniprot Id

    Q9BYC5

  • Target Species

    Human

  • Target Name

    FUT8

  • Target Full Name

    Alpha-(1,6)-fucosyltransferase

  • Target Function

    Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.

  • Target Subcellular Location

    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.

  • Target Protein Families

    Glycosyltransferase 23 family

  • Target Synonyms

    6-fucosyltransferase; Alpha (1,6) fucosyltransferase; Alpha-(1,6)-fucosyltransferase; Alpha1 6FucT; alpha1-6FucT; Fucosyltransferase 8 (alpha (1,6) fucosyltransferase) ; Fucosyltransferase 8; FUT8; FUT8_HUMAN; GDP fucose glycoprotein fucosyltransferase; GDP L Fuc:N acetyl beta D glucosaminide alpha1,6 fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1; Glycoprotein 6 alpha L fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase; MGC26465

  • Target Background

    This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.

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