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Rabbit anti-Human ZMYM3 Polyclonal Antibody

The antibody against ZMYM3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human ZMYM3 (NP_001164634.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-03362A

The antibody against ZMYM3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human ZMYM3 (NP_001164634.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-03362A ClonalityPolyclonal
Host SpeciesRabbitTarget NameZMYM3
Target SynonymsMYM; XFIM; ZNF261; DXS6673E; ZNF198L2; ZMYM3FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLaApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human ZMYM3 (NP_001164634.1).Target SpeciesHuman
Immunogen SequenceLLEPLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEELPQGQPQSPNAPPSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSVSQRAUniprot IDQ14202
Background Information
  • Uniprot Id

    Q14202

  • Target Species

    Human

  • Target Name

    ZMYM3

  • Target Full Name

    Zinc finger MYM-type protein 3

  • Target Function

    Plays a role in the regulation of cell morphology and cytoskeletal organization.

  • Target Involvement

    A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?).

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta.

  • Target Synonyms

    DXS6673E; KIAA0385; MYM; XFIM; ZFP261; Zinc finger MYM type 3; Zinc finger MYM type protein 3; Zinc finger MYM-type protein 3; Zinc finger protein 261; ZMYM 3; Zmym3; ZMYM3_HUMAN; ZNF 261; ZNF198L2; ZNF261

  • Target Background

    This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene.

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