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The antibody against OSBPL10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human OSBPL10 (NP_060254.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against OSBPL10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human OSBPL10 (NP_060254.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03507A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OSBPL10 |
| Target Synonyms | ORP10; OSBP9; OSBPL10 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, A-431, A-549, HT-29 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human OSBPL10 (NP_060254.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9BXB5 | Immunogen Sequence |
Uniprot Id
Q9BXB5
Target Species
Human
Target Name
OSBPL10
Target Full Name
Oxysterol-binding protein-related protein 10
Target Function
Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (Probable). Plays a role in negative regulation of lipid biosynthesis. Negatively regulates APOB secretion from hepatocytes. Binds cholesterol and acidic phospholipids. Also binds 25-hydroxycholesterol. Binds phosphatidylserine.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
OSBP family
Target Synonyms
FLJ20363 ; ORP-10; ORP10 ; OSB10_HUMAN; OSBP related protein 10; OSBP-related protein 10; OSBP9 ; OSBPL 10; OSBPL10; Oxysterol binding protein like 10; Oxysterol binding protein related protein 10; Oxysterol-binding protein-related protein 10
Target Background
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms have been found for this gene.
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