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The antibody against DLG3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 464-817 of human DLG3 (NP_066943.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against DLG3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 464-817 of human DLG3 (NP_066943.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-03886A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DLG3 |
| Target Synonyms | MRX; XLMR; MRX90; NEDLG; SAP102; XLID90; PPP1R82; DLG3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, 293T, K-562, Mouse brain | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 464-817 of human DLG3 (NP_066943.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q92796 | Immunogen Sequence |
Uniprot Id
Q92796
Target Species
Human
Target Name
DLG3
Target Full Name
Disks large homolog 3
Target Function
Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
Target Involvement
Mental retardation, X-linked 90 (MRX90)
Target Protein Families
MAGUK family
Target Synonyms
bA291O7.3; bA291O7.3 discs large Drosophila homolog 3 neuroendocrine dlg; Discs large Drosophila homolog 3; Discs large homolog 3 neuroendocrine dlg Drosophila; Discs large homolog 3; Discs large homolog 3 Drosophila; Discs, large homolog 3 (Drosophila); Disks large homolog 3; DLG 3; Dlg3; DLG3_HUMAN; KIAA1232; mKIAA1232; MRX 90; MRX; MRX90; NE Dlg ; NEDLG; Neuroendocrine dlg ; Neuroendocrine-DLG; OTTHUMP00000023475; OTTHUMP00000023476; OTTHUMP00000023477; SAP 102; SAP-102; SAP102; Synapse associated protein 102; Synapse-associated protein 102; XLMR
Target Background
This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described.
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