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Rabbit anti-Human CLEC11A Polyclonal Antibody

The antibody against CLEC11A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-323 of human CLEC11A (NP_002966.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04093A

The antibody against CLEC11A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-323 of human CLEC11A (NP_002966.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04093A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCLEC11A
Target SynonymsP47; SCGF; LSLCL; CLECSF3; CLEC11AFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive Samples22Rv1, A-549, JurkatApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 22-323 of human CLEC11A (NP_002966.1).Target SpeciesHuman
Uniprot IDQ9Y240Immunogen Sequence
Background Information
  • Uniprot Id

    Q9Y240

  • Target Species

    Human

  • Target Name

    CLEC11A

  • Target Full Name

    C-type lectin domain family 11 member A

  • Target Function

    Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone.

  • Target Subcellular Location

    Cytoplasm. Secreted.

  • Target Tissue Specificity

    Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.

  • Target Synonyms

    C type (calcium dependent; carbohydrate recognition domain) lectin; superfamily member 3; C type lectin domain family 11 member A; C type lectin superfamily member 3; C-type lectin domain family 11 member A; C-type lectin superfamily member 3; CLC11_HUMAN; CLEC11A; CLECSF3; LSLCL; Lymphocyte secreted C type lectin; Lymphocyte secreted C-type lectin; lymphocyte secreted long form of C type lectin; p47; Stem cell growth factor; stem cell growth factor lymphocyte secreted C type lectin

  • Target Background

    This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.

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