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The antibody against CTSZ was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human CTSZ (NP_001327.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CTSZ was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human CTSZ (NP_001327.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04304A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CTSZ |
| Target Synonyms | CTSX; CTSZ | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse kidney, 22Rv1, Mouse liver, Rat thymus, SKOV3, SW480, THP-1 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human CTSZ (NP_001327.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UBR2 | Immunogen Sequence |
Uniprot Id
Q9UBR2
Target Species
Human
Target Name
CTSZ
Target Full Name
Cathepsin Z
Target Function
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. Capable of producing kinin potentiating peptides.
Target Subcellular Location
Lysosome.
Target Protein Families
Peptidase C1 family
Target Tissue Specificity
Widely expressed.
Target Synonyms
Carboxypeptidase LB; Cathepsin B2; Cathepsin IV; Cathepsin P; Cathepsin X; Cathepsin X precursor; Cathepsin Y; Cathepsin Z; Cathepsin Z precursor; Cathepsin Z1; CathepsinP; CathepsinX; CathepsinZ; CATZ_HUMAN; CTSX; CTSZ; Cysteine type carboxypeptidase; FLJ17088; Lysosomal carboxypeptidase B; Preprocathepsin P; PreprocathepsinP
Target Background
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.
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