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Rabbit anti-Human CNN3 Polyclonal Antibody

The antibody against CNN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 220-329 of human CNN3 (NP_001830.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-04311A

The antibody against CNN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 220-329 of human CNN3 (NP_001830.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-04311A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCNN3
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.
Purification MethodAffinity purificationPositive Samples293T, Mouse brain, Mouse lung, Mouse testis, Rat lung
ApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 220-329 of human CNN3 (NP_001830.1).Target SpeciesHuman
Immunogen SequenceLAPGTRRDIYDQKLTLQPVDNSTISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGEYQDDYPRDYQYSDQGIDYUniprot IDQ15417
Background Information
  • Uniprot Id

    Q15417

  • Target Species

    Human

  • Target Name

    CNN3

  • Target Full Name

    Calponin-3

  • Target Function

    Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

  • Target Protein Families

    Calponin family

  • Target Tissue Specificity

    Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    Acidic calponin 3; acidic isoform; Calponin 3 acidic; Calponin 3; Calponin acidic; Calponin acidic isoform; Calponin; Calponin-3; Calponin3; CNN 3; Cnn3; CNN3_HUMAN; dJ639P13.2.2; OTTHUMP00000012470; OTTHUMP00000012471

  • Target Background

    This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction.

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