Rabbit anti-Human AS3MT Polyclonal Antibody

The antibody against AS3MT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 216-375 of human AS3MT (NP_065733.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04614A

Number

Cat.No	ADA-04614A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	AS3MT
Target Synonyms	CYT19; AS3MT	Form	Liquid
Species Reactivity	Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse spleen	Application	ELISA, WB

Cat.No

ADA-04614A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

AS3MT

Target Synonyms

CYT19; AS3MT

Form

Liquid

Species Reactivity

Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse spleen

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 216-375 of human AS3MT (NP_065733.2).	Target Species	Human
Immunogen Sequence	LAVLAQKIGFCPPRLVTANLITIQNKELERVIGDCRFVSATFRLFKHSKTGPTKRCQVIYNGGITGHEKELMFDANFTFKEGEIVEVDEETAAILKNSRFAQDFLIRPIGEKLPTSGGCSALELKDIITDPFKLAEESDSMKSRCVPDAAGGCCGTKKSC	Uniprot ID	Q9HBK9

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 216-375 of human AS3MT (NP_065733.2).

Target Species

Human

Immunogen Sequence

LAVLAQKIGFCPPRLVTANLITIQNKELERVIGDCRFVSATFRLFKHSKTGPTKRCQVIYNGGITGHEKELMFDANFTFKEGEIVEVDEETAAILKNSRFAQDFLIRPIGEKLPTSGGCSALELKDIITDPFKLAEESDSMKSRCVPDAAGGCCGTKKSC

Uniprot ID

Q9HBK9

Background Information

Uniprot Id

Q9HBK9
Target Species

Human
Target Name

AS3MT
Target Full Name

Arsenite methyltransferase
Target Function

Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH.
Target Subcellular Location

Cytoplasm, cytosol.
Target Protein Families

Methyltransferase superfamily, Arsenite methyltransferase family
Target Synonyms

2310045H08Rik; Arsenic (+3 oxidation state) methyltransferase; Arsenite methyltransferase; As3mt; AS3MT_HUMAN; C10ORF32; CYT19; Cyt19 protein; Hypothetical protein C10orf32; Methylarsonite methyltransferase; Methyltransferase cyt19; OTTHUMP00000020384; RP11-753C18.6; S adenosylmethionine arsenic (III) methyltransferase; S-adenosyl-L-methionine:arsenic(III) methyltransferase
Target Background

AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).

Rabbit anti-Human AS3MT Polyclonal Antibody

Specifications

Immunogen Information

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