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The antibody against WDR12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human WDR12 (NP_060726.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against WDR12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human WDR12 (NP_060726.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05029A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WDR12 |
| Target Synonyms | YTM1; WDR12 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A431, Jurkat | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human WDR12 (NP_060726.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9GZL7 | Immunogen Sequence |
Uniprot Id
Q9GZL7
Target Species
Human
Target Name
WDR12
Target Full Name
Ribosome biogenesis protein WDR12
Target Function
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Target Subcellular Location
Nucleus, nucleolus. Nucleus, nucleoplasm.
Target Protein Families
WD repeat WDR12/YTM1 family
Target Synonyms
FLJ10881; FLJ12719; FLJ12720; OTTHUMP00000163754; Ribosome biogenesis protein WDR12; WD repeat containing protein 12; WD repeat domain 12; WD repeat-containing protein 12; WDR 12; Wdr12; WDR12_HUMAN; YTM1
Target Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.
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