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The antibody against NHS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human NHS (NP_938011.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NHS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human NHS (NP_938011.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05157A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NHS |
| Target Synonyms | CXN; SCML1; CTRCT40; NHS | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, Raji | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human NHS (NP_938011.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6T4R5 | Immunogen Sequence |
Uniprot Id
Q6T4R5
Target Species
Human
Target Name
NHS
Target Full Name
Actin remodeling regulator NHS
Target Function
May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development.
Target Involvement
Nance-Horan syndrome (NHS); Cataract 40 (CTRCT40)
Target Subcellular Location
[Isoform 1]: Apical cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell junction, tight junction. Cell junction, focal adhesion. Note=Colocalizes with the tight junction protein TJP1 in epithelial cells. Localizes to the leading edge of lamellipodia in motile cells.; [Isoform 3]: Cytoplasm.
Target Protein Families
NHS family
Target Tissue Specificity
Detected at low levels in all tissues analyzed. Detected in fetal and adult brain, lens, retina, retinal pigment epithelium, placenta, lymphocytes and fibroblasts. Levels in retinal pigment epithelium, placenta, lymphocytes, and fibroblasts are very low.
Target Synonyms
NHS; Nance-Horan syndrome protein; Congenital cataracts and dental anomalies protein
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