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The antibody against KCNJ15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 221-375 of human KCNJ15 (NP_002234.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against KCNJ15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 221-375 of human KCNJ15 (NP_002234.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-05164A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KCNJ15 |
| Target Synonyms | IRKK; KIR1.3; KIR4.2; KCNJ15 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, 293T, Mouse liver, Rat liver | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 221-375 of human KCNJ15 (NP_002234.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | VTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQSNV | Uniprot ID | Q99712 |
Uniprot Id
Q99712
Target Species
Human
Target Name
KCNJ15
Target Full Name
ATP-sensitive inward rectifier potassium channel 15
Target Function
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ15 subfamily
Target Synonyms
KCNJ15; KCNJ14; ATP-sensitive inward rectifier potassium channel 15; Inward rectifier K(+ channel Kir1.3; Inward rectifier K(+ channel Kir4.2; Potassium channel, inwardly rectifying subfamily J member 15
Target Background
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene.
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