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The antibody against RALGPS1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RALGPS1 (NP_055451.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RALGPS1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RALGPS1 (NP_055451.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05431A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RALGPS1 |
| Target Synonyms | RALGEF2; RALGPS1A; RALGPS1 | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Rat thymus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RALGPS1 (NP_055451.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q5JS13 | Immunogen Sequence |
Uniprot Id
Q5JS13
Target Species
Human
Target Name
RALGPS1
Target Full Name
Ras-specific guanine nucleotide-releasing factor RalGPS1
Target Function
Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization. Guanine nucleotide exchange factor for.
Target Subcellular Location
Cytoplasm. Cell membrane. Note=Associates with membranes through the PH domain.
Target Tissue Specificity
Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, p
Target Research Area
Signal Transduction
Target Synonyms
RALGPS1; KIAA0351; RALGEF2; Ras-specific guanine nucleotide-releasing factor RalGPS1; Ral GEF with PH domain and SH3-binding motif 1; Ral guanine nucleotide exchange factor 2; RalGEF 2; RalA exchange factor RalGPS1
Target Background
Enables guanyl-nucleotide exchange factor activity. Involved in regulation of Ral protein signal transduction. Predicted to be located in cytoplasm and plasma membrane.
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