Rabbit anti-Human TSHB Polyclonal Antibody

The antibody against TSHB was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TSHB (NP_000540.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05586A

Number

Cat.No	ADA-05586A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	TSHB
Target Synonyms	TSH-B; TSH-BETA; TSHB	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, Rat brain, HT-29, LO2, Mouse brain, Mouse liver, Rat kidney, Rat liver	Application	ELISA, WB

Cat.No

ADA-05586A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

TSHB

Target Synonyms

TSH-B; TSH-BETA; TSHB

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, Rat brain, HT-29, LO2, Mouse brain, Mouse liver, Rat kidney, Rat liver

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TSHB (NP_000540.2).	Target Species	Human
Immunogen Sequence	YCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV	Uniprot ID	P01222

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TSHB (NP_000540.2).

Target Species

Human

Immunogen Sequence

YCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV

Uniprot ID

P01222

Background Information

Uniprot Id

P01222
Target Species

Human
Target Name

TSHB
Target Full Name

Thyrotropin subunit beta
Target Function

Indispensable for the control of thyroid structure and metabolism.
Target Subcellular Location

Secreted.
Target Protein Families

Glycoprotein hormones subunit beta family
Target Research Area

Signal Transduction
Target Synonyms

TSHBThyrotropin subunit beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain; Thyrotropin alfa
Target Background

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

Rabbit anti-Human TSHB Polyclonal Antibody

Specifications

Immunogen Information

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