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The antibody against RABL3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human RABL3 (NP_776186.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against RABL3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human RABL3 (NP_776186.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-05714A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RABL3 |
| Target Synonyms | PNCA5; RABL3 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | MCF7, Mouse brain, Mouse lung, Mouse testis | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human RABL3 (NP_776186.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q5HYI8 | Immunogen Sequence |
Uniprot Id
Q5HYI8
Target Species
Human
Target Name
RABL3
Target Full Name
Rab-like protein 3
Target Function
Required for KRAS signaling regulation and modulation of cell proliferation. Regulator of KRAS prenylation, and probably prenylation of other small GTPases. Required for lymphocyte development and function. Not required for myeloid cell development.
Target Protein Families
Small GTPase superfamily, Rab family
Target Synonyms
RAB member of RAS oncogene family like 3; Rab-like protein 3; RABL3; RABL3_HUMAN
Target Background
Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Involved in regulation of Ras protein signal transduction and regulation of protein lipidation. Predicted to be active in endomembrane system. Implicated in pancreatic cancer.
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