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The antibody against PMF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human PMF1 (NP_009152.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PMF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human PMF1 (NP_009152.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05753A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PMF1 |
| Target Synonyms | PMF1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, HepG2, Jurkat | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human PMF1 (NP_009152.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6P1K2 | Immunogen Sequence |
Uniprot Id
Q6P1K2
Target Species
Human
Target Name
PMF1
Target Full Name
Polyamine-modulated factor 1
Target Function
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
Target Subcellular Location
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Target Tissue Specificity
Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver.
Target Synonyms
NNF1R; PMF 1; PMF-1; Pmf1; PMF1_HUMAN; Polyamine modulated factor 1; Polyamine-modulated factor 1
Target Background
Enables leucine zipper domain binding activity and transcription coactivator activity. Involved in chromosome segregation. Located in Golgi apparatus; kinetochore; and nucleoplasm. Part of MIS12/MIND type complex. Implicated in bladder carcinoma and urinary bladder cancer.
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