Rabbit anti-Human CNTN6 Polyclonal Antibody

The antibody against CNTN6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human CNTN6 (NP_055276.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05758A

Number

Cat.No	ADA-05758A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CNTN6
Target Synonyms	NB3; CNTN6	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, U-87MG	Application	ELISA, WB

Cat.No

ADA-05758A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CNTN6

Target Synonyms

NB3; CNTN6

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human CNTN6 (NP_055276.1).	Target Species	Human
Immunogen Sequence	DGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTIL	Uniprot ID	Q9UQ52

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human CNTN6 (NP_055276.1).

Target Species

Human

Immunogen Sequence

DGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTIL

Uniprot ID

Q9UQ52

Background Information

Uniprot Id

Q9UQ52
Target Species

Human
Target Name

CNTN6
Target Full Name

Contactin-6
Target Function

Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.
Target Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families

Immunoglobulin superfamily, Contactin family
Target Tissue Specificity

Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.
Target Synonyms

CNTN 6; CNTN6; CNTN6_HUMAN; Contactin 6 precursor; Contactin-6; Contactin6; hNB 3; hNB-3; hNB3; MGC133256; NB 3; NB3; Neural adhesion molecule; Neural recognition molecule NB 3; Neural recognition molecule NB-3
Target Background

The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human CNTN6 Polyclonal Antibody

Specifications

Immunogen Information

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