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Rabbit anti-Human KIF5C Polyclonal Antibody

The antibody against KIF5C was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 510-590 of human KIF5C (NP_004513.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06029A

The antibody against KIF5C was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 510-590 of human KIF5C (NP_004513.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-06029A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKIF5C
Target SynonymsKINN; NKHC; NKHC2; CDCBM2; NKHC-2; KIF5CFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHT-29, OVCAR3ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 510-590 of human KIF5C (NP_004513.1).Target SpeciesHuman
Immunogen SequenceRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYUniprot IDO60282
Background Information
  • Uniprot Id

    O60282

  • Target Species

    Human

  • Target Name

    KIF5C

  • Target Full Name

    Kinesin heavy chain isoform 5C

  • Target Function

    Involved in synaptic transmission. Mediates dendritic trafficking of mRNAs. Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.

  • Target Involvement

    Cortical dysplasia, complex, with other brain malformations 2 (CDCBM2)

  • Target Subcellular Location

    Cytoplasm, cytoskeleton. Cell projection, dendrite.

  • Target Protein Families

    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, Kinesin subfamily

  • Target Tissue Specificity

    Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary.

  • Target Synonyms

    CDCBM2; FLJ44735; KIAA0531; KIF 5C; Kif5c; KIF5C protein; KIF5C_HUMAN; Kinesin family member 5C; Kinesin heavy chain isoform 5C; Kinesin heavy chain neuron specific 2; Kinesin heavy chain neuron specific; Kinesin heavy chain neuron-specific 2; Kinesin5C; KINN; MGC111478; NKHC 2; NKHC; NKHC-2; NKHC2

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