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The antibody against RIN2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RIN2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06034A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RIN2 |
| Target Synonyms | MACS; RASSF4; RIN2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, Mouse kidney, 293T, A-549, HepG2 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8WYP3 | Immunogen Sequence |
Uniprot Id
Q8WYP3
Target Species
Human
Target Name
RIN2
Target Full Name
Ras and Rab interactor 2
Target Function
Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP.
Target Involvement
MACS syndrome (MACS)
Target Subcellular Location
Cytoplasm.
Target Protein Families
RIN (Ras interaction/interference) family
Target Tissue Specificity
Widely expressed. Expressed in heart, kidney, lung placenta. Expressed at low level in skeletal muscle, spleen and peripheral blood.
Target Synonyms
RIN2; RASSF4; Ras and Rab interactor 2; Ras association domain family 4; Ras inhibitor JC265; Ras interaction/interference protein 2
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