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The antibody against SCNN1D was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 540-680 of human SCNN1D (NP_001123885.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SCNN1D was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 540-680 of human SCNN1D (NP_001123885.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06460A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SCNN1D |
| Target Synonyms | ENaCd; SCNED; dNaCh; ENaCdelta; SCNN1D | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, A-549, MCF7, Mouse brain, Mouse liver, Rat liver, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 540-680 of human SCNN1D (NP_001123885.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | GVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSARHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGEQGLPHQSHRQRSSLAKINIVYQELNYRSVEEA | Uniprot ID | P51172 |
Uniprot Id
P51172
Target Species
Human
Target Name
SCNN1D
Target Full Name
Epithelial sodium channel subunit delta
Target Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Amiloride-sensitive sodium channel (TC 1.A.6) family, SCNN1D subfamily
Target Synonyms
Amiloride sensitive sodium channel subunit delta; Amiloride-sensitive sodium channel subunit delta; Delta ENaC; Delta NaCH; Delta-ENaC; Delta-NaCH; DNACH; ENaC Delta; ENaCD; ENaCdelta; Epithelial Na(+) channel subunit delta; MGC149710; MGC149711; Nonvoltage gated sodium channel 1 subunit delta; Nonvoltage-gated sodium channel 1 subunit delta; SCNED; SCNN1D; SCNND_HUMAN; Sodium channel, nonvoltage gated 1, delta
Target Background
Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Located in actin cytoskeleton and plasma membrane.
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