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The antibody against ZNF143 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 437-638 of human ZNF143 (NP_003433.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ZNF143 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 437-638 of human ZNF143 (NP_003433.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06936A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZNF143 |
| Target Synonyms | SBF; STAF; pHZ-1; ZNF143 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2, Mouse liver, Mouse spleen, Rat liver, Rat testis, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 437-638 of human ZNF143 (NP_003433.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P52747 | Immunogen Sequence |
Uniprot Id
P52747
Target Species
Human
Target Name
ZNF143
Target Full Name
Zinc finger protein 143
Target Function
Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.
Target Subcellular Location
Nucleus.
Target Protein Families
GLI C2H2-type zinc-finger protein family
Target Tissue Specificity
Expressed in all tissues tested, with the strongest expression in ovary.
Target Synonyms
ZNF143; SBF; STAF; Zinc finger protein 143; SPH-binding factor; Selenocysteine tRNA gene transcription-activating factor; hStaf
Target Background
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of snRNA transcription by RNA polymerase II. Predicted to be located in nucleoplasm.
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