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The antibody against GRHPR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-328 of human GRHPR (NP_036335.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against GRHPR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-328 of human GRHPR (NP_036335.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-06958A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRHPR |
| Target Synonyms | PH2; GLXR; GLYD; GRHPR | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, 293T, HepG2, PC-3 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 100-328 of human GRHPR (NP_036335.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UBQ7 | Immunogen Sequence |
Uniprot Id
Q9UBQ7
Target Species
Human
Target Name
GRHPR
Target Full Name
Glyoxylate reductase/hydroxypyruvate reductase
Target Function
Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
Target Involvement
Hyperoxaluria primary 2 (HP2)
Target Protein Families
D-isomer specific 2-hydroxyacid dehydrogenase family
Target Tissue Specificity
Ubiquitous. Most abundantly expressed in the liver.
Target Synonyms
GLXR; glycerate 2 dehydrogenase ; GLYD; Glyoxylate reductase/hydroxypyruvate reductase; Grhpr; GRHPR_HUMAN; OTTHUMP00000021379; OTTHUMP00000021380; OTTHUMP00000046131; PH 2; PH2; Primary hyperoxaluria type 2
Target Background
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.
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