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Rabbit anti-Human PNLDC1 Polyclonal Antibody

The antibody against PNLDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human PNLDC1 (NP_775787.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07132A

The antibody against PNLDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human PNLDC1 (NP_775787.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-07132A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePNLDC1
Target SynonymsSPGF57; Trimmer; HsPNLDC1; PNLDC1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse brain, Mouse liver, Mouse testis, Raji, Rat testis, U-251MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human PNLDC1 (NP_775787.1).Target SpeciesHuman
Uniprot IDQ8NA58Immunogen Sequence
Background Information
  • Uniprot Id

    Q8NA58

  • Target Species

    Human

  • Target Name

    PNLDC1

  • Target Full Name

    Poly(A)-specific ribonuclease PNLDC1

  • Target Function

    3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. May act as a regulator of multipotency in embryonic stem cells.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Single-pass membrane protein.

  • Target Protein Families

    CAF1 family

  • Target Synonyms

    oly(A)-specific ribonuclease PARN-like domain-containing protein 1; PNDC1_HUMAN; PNLDC1; poly(A)-specific ribonuclease (PARN)-like domain containing 1; Poly(A)-specific ribonuclease PARN-like domain-containing protein 1; RP1-195P10.1

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