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Rabbit anti-Human ARPC4 Polyclonal Antibody

The antibody against ARPC4 was raised in rabbit using the Recombinant Human Actin-related protein 2/3 complex subunit 4 protein (2-168AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-07335A

The antibody against ARPC4 was raised in rabbit using the Recombinant Human Actin-related protein 2/3 complex subunit 4 protein (2-168AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-07335A ClonalityPolyclonal
Host SpeciesRabbitTarget NameARPC4
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Actin-related protein 2/3 complex subunit 4 protein (2-168AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP59998
Background Information
  • Uniprot Id

    P59998

  • Target Species

    Human

  • Target Name

    ARPC4

  • Target Full Name

    Actin-related protein 2/3 complex subunit 4

  • Target Function

    Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).

  • Target Subcellular Location

    Cytoplasm, cytoskeleton. Cell projection. Nucleus.

  • Target Protein Families

    ARPC4 family

  • Target Synonyms

    Actin related protein 2/3 complex subunit 4 ; Actin related protein 2/3 complex subunit 4 20 kD; Actin related protein 2/3 complex subunit 4 20kDa; Actin related protein 2/3 complex; 20-KD subunit; Actin-related protein 2/3 complex subunit 4; ARC20; Arp2/3 complex 20 kDa subunit; Arp2/3 protein complex subunit p20 ; ARPC 4; ARPC4; ARPC4_HUMAN; MGC13544; OTTHUMP00000165252 ; OTTHUMP00000207520; p20 Arc; p20-ARC; p20ARC

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